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Although the details differ for different Csp3s, the kinetics of Cu I binding are generally quite fast but only for an initial phase, with the kinetics of Cu I removal by a high affinity Cu(I) chelator very slow, beyond the first couple mol equivalents of Cu I

The gap between 'orally active in rats' and 'clinically viable in humans' is where most compounds failand Dihexa sits directly in that gap

Furthermore, it plays a pivotal role in preserving, regenerating, and remodelling impaired tissues

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Tendon and ligament fibroblast cultures examining outgrowth rate, collagen organization, and growth-factor receptor expression after mechanical or chemical injury