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This is considered to be the rate limiting step because it is dependent on the bioavailability of cysteine and the activity of GCL, the latter of which is modified by competitive inhibition by reduced glutathione (GSH) [3134]

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For laboratory research use only.

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2) This study performed by Ummadisetty et al investigated the behavioral and molecular effects of the peptide dermorphin [D-Arg2, Lys4] (14) amide (DALDA) in a rat model of frostbite-induced neuropathic pain

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