Higuchi T, Abe M, Yamazaki T et al (2016) Levocarnitine improves cardiac function in hemodialysis patients with left ventricular hypertrophy: a randomized controlled trial
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doi: 10.1007/s10863-023-09968-5 Summary Keywords ferroptosis, endoplasmic reticulum stress, rheumatoid arthritis, lipid peroxidation, reactive oxygen species, unfolded protein response Citation Ao Q, Hu H and Huang Y (2024) Ferroptosis and endoplasmic reticulum stress in rheumatoid arthritis
MSU crystals activate the Mitogen-activated protein kinase (MAPK)/NF-B and Janus kinase-1 (JAK-1) - signal transducers and activators of transcription1/3 (STAT1/3) signaling pathways in macrophages, inducing M1 macrophages polarization and releasing M1 macrophages-associated factors TNF, IL-1, and IL-6 (66, 70)
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Ascorbate peroxidase (APX), ascorbic acid (ASC), glutathione reductase (GR), and glutathione (GSH) belong to ascorbate-glutathione cycle, which is an essential pathway for plants to avoid oxidative burst (Cengiz et al., 2020)