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22 , e13082 (2021)

Fortner, C

& Englert, C

Simone Tan Institution: Singapore Institute for Neuroregeneration Result: Peptide-based circadian entrainers (like vasoactive intestinal peptide) combined with autologous stem cells post-plasmapheresis led to substantial reduction in insomnia severity index scores and improved subjective sleep quality in clinical pilot trials

Spinal decompression therapy is designed to reduce pressure within spinal discs

Consistent with the notion that GSH per se does not regulate mTORC1 and the ISR, depletion of intracellular GSH exacerbated the loss of mTORC1 signaling upon cystine deprivation, but was without observable effect in the presence of cystine (Fig