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Although modulating endothelium-derived vasoactive factors, antioxidation and regulating programmed cell death are beneficial for improving CC endothelial dysfunction related to MetS, limited literature evidence, low bioavailability, lack of cell specificity and low clinical efficacy as well as other factors have restricted the drug development based on these targets

Retrieved from Qian, L., Wang, W., Zhou, Y., & Ma, J

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doi: 10.1002/mds.26088

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