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Safety and efficacy of tapentadol ER in patients with painful diabetic peripheral neuropathy: results of a randomized-withdrawal, placebo-controlled trial
Chem Rev 121:32973351 White BH, Whalen K, Kriksciukaite K, Alargova R, Au Yeung T, Bazinet P, Brockman A, DuPont M, Oller H et al (2019) Discovery of an SSTR2-targeting maytansinoid conjugate (PEN-221) with potent activity in vitro and in vivo
For example, dissolvable poly (-glutamic acid) microneedles co-loaded with EGCG and L-ascorbic acid retained 95% EGCG and 93% antioxidant activity after 4 weeks at 4 C, and delivered 63% EGCG and 62% ascorbic acid up to 600 m into the skin