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En un modelo de herida se describi una ventana de dosis : concentraciones bajas (~0,1 M) se asociaron con menor trans-diferenciacin de fibroblastos a miofibroblastos y menor contraccin, mientras que concentraciones mayores (~0,5 M) atenuaron ese efecto, lo que sugiere dependencia de dosis (PMID 30603464)
Kurayama, R
Ferrostatin-1 and Liproxstatin-1, two well-known inhibitors of ferroptosis, for instance, have demonstrated protective benefits in both ARDS and ALI models ( 3.2 Endothelial cell dysfunction One characteristic of ARDS is endothelial cell dysfunction, which exacerbates lung injury by disrupting the alveolar-capillary barrier
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