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Local reactions may include erythema, pruritus, induration, or mild pain at the injection site, potentially affecting five to ten percent of patients

For motor neuron count, spinal cords from anesthetized rats were collected and post-fixed for 12 hours in 4% PFA

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Results maintenance requires ongoing or periodic use - stopping treatment leads to gradual regression over 2-6 months as new collagen formation stops and natural aging resumes

Fatigue or Dizziness: Transient lethargy has been noted early on, possibly from metabolic shifts or inflammation reduction