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In addition, CAT4001 compound has been shown to decrease ROS production, normalize mitochondrial length, and improve mitochondrial function in dorsal root ganglion (DRG) derived neurons from FRDAs mice [284], thus expanding the therapeutic potential also in the field of neurodegenerative diseases

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Sphingosine-1-phosphate protects endothelial glycocalyx by inhibiting syndecan-1 shedding

Researchers often compare or combine them in experimental models to investigate complementary biological pathways

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