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As fat cells grow larger, they begin to overproduce an enzyme called NNMT (nicotinamide N-methyltransferase)

Body Weight/Size Body weight or size is another factor

Children presenting neurological signs or symptoms, those unable to take oral medication, individuals with known malabsorption syndromes, infants under 6 months old, and patients using medications that may interfere with vitamin B12 absorption are typically treated with a parenteral protocol (1)

Any references to biological activity are provided strictly for research context and must not be interpreted as claims of safety, efficacy, or intended human use

IV folic acid for severe folate deficiency

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