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Chang may taper your schedule to monthly boostersor pause them altogether if your levels remain in a healthy range
On/off cycling here is driven by caution, not by tolerance data: because there is no long-term human safety record, building in scheduled off periods is the conservative research default
Further, NICE and the BNF says that if there are neurological symptoms present, then every other day injections are the recommended treatment, so all the points you make about B12 being stored and sufficient are not really relevant
Pancreatitis and gallbladder issues: Severe abdominal pain that radiates to the back, nausea, fever, or vomiting while using GLP-1s may indicate inflammation of the pancreas, while upper right abdominal pain, jaundice, fever, and nausea can be due to gallbladder issues such as gallstones
Pregnant or breastfeeding women should avoid both compounds
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