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however, this benefit needs more research

Nevertheless, in cases of severe deficiency with neurological sequelae, we suggest that IM B12 is used in the first instance to replenish body stores with the treatment regimen, including dosage and formulation, optimised to keep the patient free of symptoms and tailored to the metabolic response of not only plasma B12 levels, but also confirmatory testing of homocysteine, methionine, and methylmalonic acid levels

This dual action supports both immediate cognitive performance and long-term brain health

CNS Drugs, 29(5), 343351

(c) alcohol intake is forbidden during BV therapies

Despite mixed evidence on statin use and dementia risk 42,43 , our results indicate a possible increased risk with baseline statin use