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An exemplary batch of gel formulation containing, for example, 1.5% of a JNK inhibitor described herein is prepared by dissolving Poloxamer 407 (BASF Corp.) in 50 mM Tris buffer and 77 mM NaCl solution with a pH between 5.5-8.0

Our results suggests that the chemical stability of NAC, the active pharmaceutical ingredient, is well within the guidelines set forth in United States Pharmacopeia Chapter (90% to 110% stated potency) for both temperatures ( Table 4 )

Power outages present unexpected room temperature exposure scenarios