B12 injections may help alleviate symptoms of depression and improve overall mood
But for patients who have done the foundational work diet, movement, sleep, lab optimization and are still hitting a wall with fat metabolism or body composition, it may be a worthwhile piece of the puzzle
Preclinical studies demonstrate elevated intracellular NAD+ levels following NNMT inhibition, suggesting a role in metabolic energy regulation
Namely, it is always applied alone (Sikiric et al., 1993
It is not approved by the FDA or any other regulatory agency for medical or diagnostic use
The honest answer is that the evidence base is still developing, which is true of many treatments that are now standard of care, said Dr Anant Vinjamoori, chief medical officer of Hims