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Neurological Benefits: Methylcobalamin has been shown to have direct neurological benefits

This architecture creates an extraordinarily high binding affinity (pK = 16.44), roughly 10 million times stronger than other tripeptides and comparable to albumins copper binding

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It functions as a cofactor for lysyl oxidase (the enzyme responsible for collagen cross-linking and stabilization), ceruloplasmin (a copper transport protein with antioxidant activity), and superoxide dismutase (SOD, a primary antioxidant defense enzyme)

[DOI] [PMC free article] [PubMed] [Google Scholar] [87].Shefner R, Kleiner G, Turken A

Most common possible reasons for incorrect predictions were post-hoc identified as artifacts (n = 10), stenosis of vessels (n = 2) and old infarcts (n = 2)