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The bioactive chemicals responsible for this effect are ursolic acid and oleanolic acid

Nrf1/2 maintains mitochondrial homeostasis by modulating the nuclear gene expression of components within the oxidative phosphorylation system (Scarpulla, 2002a,b)

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Lets look at the details of what this means: What is the impact of MTHFR C677T: The MTHFR C677T variant changes the enzyme structure in a way that makes it break down faster at normal body temperature (more thermolabile )

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