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However, in the pivotal Phase IIb trial, it failed to demonstrate statistically significant weight loss compared to placebo at the primary endpoint, leading the developer (Metabolic Pharmaceuticals Ltd.) to terminate the commercial program

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Current Pharmaceutical Design , 2020 Cytoprotective Effects on the Gut: Orally administered BPC-157 has shown promise in protecting the mucosal lining of the stomach and intestines , though oral bioavailability is debated