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OTA toxicity may be involved in the development of certain kidney diseases through generation of oxidative stress [64]
SFN also induces a series of biological defense genes, including phase II detoxification/antioxidant enzymes and antioxidant molecules such as glutathione (GSH, L--glutamyl-L-cysteinyl-glycine), and suppresses inflammation via the inhibition of nuclear factor kappa B (NF-B) and the activation of the transcription factor nuclear factor-erythroid 2-related factor 2 (Nrf2) (17, 18)
This leads to elevated inflammatory cytokines, elevated ROS, and recruitment of immune cells
Such consequences will ultimately hinder tissue regeneration and repair processes (Sies and Jones, 2020
Lin YT, Lin J, Liu YE, Chen YC, Liu ST, Hsu KW et al
Key Features: Contains0.9% benzyl alcoholto inhibit bacterial growth for multiple withdrawals
