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The beneficial pharmacological effects of coffee, as demonstrated by numerous scientific studies, are related to its anti-inflammatory, antioxidant, antiangiogenic, anticancer, chemoprotective and hepatoprotective properties (Doepker et al., 2022

Neutrophil elastase is a potent proteolytic enzyme secreted by neutrophils as part of the innate immune response to infection

D-Panthenol is also known as vitamin b5 that helps in proper utilization of other nutrients such as carbohydrate, fat, and protein

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Since the survey questions regarding these products changed frequently during the study period (20162022), it was not methodologically feasible to construct a consistent variable for the entire pooled dataset

[1] This interesting neuropeptide gets its name from animal research, when it was found to be able to induce deep sleep in rabbits