However, in an agonist-bound state such as was seen in the crystal structure of DHT-bound AR (PDB: 1I37 or 2AMA), H12 was held near H3 and H4 (Figure 3D)
Further, some studies suggested that TG levels in MDD patients were actually lower than those in healthy controls (95)
[DOI] [PMC free article] [PubMed] [Google Scholar] Sussmann R
This is consistent with experimental data in mice [17,18] and in the human study [19]
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Studies that show a positive association often fail to adjust for this critical variable