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doi: 10.3322/caac.21456 53 LheureuxSGourleyCVergote I and OzaAM

483 Conclusions and future directions In summary, this review delineates the multifactorial determinants underlying the pathogenesis of immunosenescence and its contributory role in diverse age-related pathologies

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Or that is what we used to think

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It acts directly on neighboring -cells to inhibit the secretion of glucagon and can also indirectly influence -cells by inhibiting the secretion of other hormones