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When used properly, it has few side effects

( Our former studies have confirmed that GSH supplementation promoted mitochondrial functions of mammalian gametes ( Moreover, the current study was limited by the lacking of DNA integrity and in vivo fertility assessment to confirm the synergistic protective effect of co-supplementation of GSH with SeNPs on the cryopreservation efficiency of bull semen

Reduced L-glutathione

A 2020 meta-analysis in Nutrients found glutathione may modestly reduce inflammatory markers (TNF-alpha, IL-6) in select populations, but heterogeneity in study design limits definitive recommendations

They thought, "Fringe." They're not fringe

Some users report transient irritability at high doses