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doi: 10.1093/femspd/ftx112 62 CornelissenC

These causes are the most common ones for spinal stenosis, but other causes include tumors of the spine, injuries, Pagets disease, too much fluoride in the body, and calcium deposits on the ligaments that run along the spine

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Additionally, around 12% of oxygen used in mitochondrial metabolism produces free radicals, which can lead to oxidative stress and even DNA damage [2]

Each time a cell divides, they shorten slightly, eventually reaching a length that triggers cellular senescence

10.1016/j.fertnstert.2012.05.031 7