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Hydroxysafflor yellow A (HYA) reduces allergic symptoms in AR mice by decreasing the levels of RORt, STAT3, and p-STAT3 while activating the Nrf2/HO-1 pathway [174]

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Similar to ROS, low to moderate levels of RNS play physiological roles in vasodilation, neurotransmission, and immune regulation, while their overproduction leads to pathological modifications of proteins, DNA, and lipids [65]

Upon request, we would be happy to supply blood work from patients that have used these products so you can see for yourself how impactful they have been