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Lower tirzepatide doses (510mg weekly) reduce GI side effect burden while still providing meaningful appetite suppression, allowing researchers to maintain protocol adherence without the nausea and vomiting that causes 1015% of subjects to discontinue at higher doses
Spain, Department of Psychiatry University Hospital of Bellvitge-IDIBELL, Barcelona: Financial support was received from Fondo de Investigacin SanitariaFIS (PI11/210) and AGAUR (2009SGR1554)
It enhanced the function of the neurotransmitter acetylcholine via muscarinic receptors [76], and affected N-methyl-D-aspartate receptors in rat models in vivo, increasing cell membrane permeability [77]