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Subsequently summarized in: Pickart L, Margolina A

Its inclusion in the Category 2 restricted list has drawn criticism from clinicians who point to its legitimate international approval record as evidence that the safety concerns cited by the FDA are inconsistent with the global clinical literature

Broad-spectrum sunscreen with SPF 30 or higher, protective clothing, and avoiding peak sun hours reduce photoaging

These are those with HIV-associated lipodystrophy

Wound Healing & Tissue Regeneration Research Clinical validation demonstrates accelerated wound closure rates exceeding 60% compared to controls across multiple injury models including chemical burns, surgical wounds, and chronic ulcers

It also stabilizes endothelial cell junctions, reducing fluid leakage and swelling