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This depletion is tightly linked to the breakdown of immune homeostasis, intestinal barrier dysfunction, and uncontrolled systemic inflammation, underscoring Clostridium s potential as a core target for microbiota-based immunotherapy

Preclinical models suggest that NRF2 activation enhances antioxidant enzyme expression, but human clinical evidence in FM is lacking (22, 23)

Liposomal glutathione, NAC, and vitamin C are physiologically aligned and safe for long-term use when taken within recommended doses

This sensation usually happens right after application and fades within a short time

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