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Importantly, although our in vitro genetic experiments identify MGST3 as a key regulatory node, our in vivo pharmacological data demonstrate that targeting the broader GST-mediated ferroptosis defense network is therapeutically effective

Ascorbic acid induces global epigenetic reprogramming to promote meiotic maturation and developmental competence of porcine oocytes

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Serum FAM19A5 levels: A novel biomarker for neuroinflammation and neurodegeneration in major depressive disorder

481 This suggests that ACSL4 initiates a cascade that links ferroptosis to pyroptosis, thereby promoting cardiac hypertrophy and responding to the hemodynamic stress induced by aortic constriction

Their findings indicated that this dual intervention led to increased plasma serotonin, dopamine, and -endorphins, which are associated with improved mood and stress resilience [241]