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ROS-induced damage to DNA may result in mutations, which in turn may contribute to cancer incidence

By contrast, within a hypoxic TME, tumor-infiltrating NK cells exhibit severe mitochondrial fragmentation, which impairs their tumor-killing capacity and immune surveillance function, thus promoting tumor immune evasion (94)

Graphical abstract Similar content being viewed by others Introduction Parkinsons disease (PD) is the second most common neurodegenerative disorder after Alzheimers disease

Al tratarse de un material para investigacin, debe manejarse con las precauciones estndar de laboratorio y sin destino de uso clnico

Astrocytic mitochondrial ROS modulate brain metabolism and mouse behaviour

Genetic depletion of MAPKAPK2 abolishes these protective effects, whereas re-expression of MAPKAPK2 restores resistance to oxidative stressinduced cellular injury