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Treatment with NAC restored the sizes of ACTL6A-KD PDOs that had been decreased, and enabled organoids regained a cystic structure (Fig

Administering hepsin to wild-type mice increases APAP tolerance and downregulates GJ expression Considering the potential clinical and medical applications, we evaluated a therapeutic strategy involving the administration of hepsin to wild-type adult mice and assessed its potential to mitigate APAP-induced liver injury