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Upon heating, these components undergo thermal degradation, producing harmful by-products

Food and Drug Administration for specific medical indications

Loss of BCKDK function resulted in hypercatabolism of Leu, Ile and Val, leading to abnormally low levels of these BCAAs in serum and in the brain (100)

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Peptide therapy as a research discipline has expanded substantially over the past two decades as analytical tools for studying these cellular mechanisms have become more refined