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CURRENT ANTI-OBESITY PHARMACOTHERAPY Anti-obesity pharmacotherapy is indicated as an adjunct to lifestyle interventions in adults with a BMI 30 kg/m 2 or a BMI 27 kg/m 2 in patients with additional weight-related comorbidities

Further, these data suggest that at acute time points following Gclc genetic deletion, compensation by NRF1 could be responsible for the dispensable role of NRF2 in GSH-depleted conditions

Our prior research established that the uptake of glutamate via EAAT3 plays a pivotal role in driving cystine uptake through xCT, contributing to GSH biosynthesis during lung tumorigenesis

Sevgin K, Erguven P