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Proc Soc Surg Aliment Tract:121, 1993

All cell lines were cultured in suspension using RPMI-1640 medium (Gibco) supplemented 10% FBS (New Zerum), under the condition of 37 C and 5% CO 2

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However, CD3 CAR T cells of LTR exhibited significantly increased mTOR and pS6 expression compared to STR, suggesting a shift from a memory-to-effector metabolic phenotype of LTR CAR T cells from pre- to post-infusion, respectively (Fig