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T.GuoL.et al (2019)

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Prior to the behavioural procedures involving auditory startle responses (ASRs), rats were handled and acclimated (5 min) to the startle boxes and background noise (65 dB white noise)

The primary role of malate is to function as a tricarboxylic acid cycle intermediate, which may play an important role in the rate of ATP production (Brendahan et al

Additionally, thiamin triphosphate (TTP) may be involved in neuronal membrane functions and nerve impulse (action potential) generation, but the exact biochemical role of TTP is still not well understood (22, 23)