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The B12-conjugated GLP-1 agonist maintained comparable blood sugar control but with significantly better tolerance, less nausea, and fewer emetic episodes in both rat and mammalian models

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Avoid other GLP-1 or GIP agonists like semaglutide or tirzepatide alongside Retatrutide due to overlapping mechanisms and compounded side effects

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In addition, L-K6, an AMP modified based on the AMP Temporin-1 CEb from Rana chensinensis, was proved to have good anti-cancer activity in vitro and was non-toxic to normal human cells

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