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Adjunctive Host-directed therapy with statins improves tuberculosis-related outcomes in mice

By blocking NNMT, 5-AMINO-1MQ encourages increased fat burning and supports lean muscle preservation, making it beneficial for weight management

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Decreased glutathione in G6PD deficiency As the only source of NADPH in the RBC is the pentose phosphate pathway, a G6PD defect causes decreased NADPH and therefore low GSH production in the RBC