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However, in several cases the sulfonation reaction can lead to formation of a more active metabolite compared to the parent compound as is the case for the hair follicle stimulant minoxidil (Buhl et al., 1990) or the diuretic agent triamterene (Mutschler et al., 1983)

Symptoms may include: Severe headache Neck stiffness Fever Nausea or vomiting Sensitivity to light (photophobia) Extreme fatigue These symptoms typically develop within several hours to a few days after an infusion

Frequently used in protocols targeting body composition, metabolic health, and sleep quality

Anthropometric and metabolic characteristics of young (non-interventional cohort) and older (interventional cohort) study subjects and differences in oxidative stress-related markers

doi: 10.1038/natrevmats.2016.68 134 SeguraJLMancheoMJZamoraF