These values are estimates only
R Met/Met individuals have higher synaptic dopamine and norepinephrine (because COMT clears them more slowly), which improves prefrontal cortex function and working memory but increases susceptibility to stress-related anxiety, pain sensitivity, and catechol estrogen accumulation
(1989) Toxicity of the cysteine-S-conjugates and mercapturic acids of dour structurally related difluoroethylenes in isolated proximal tubular cells from rat kidney uptake of the conhugates and activation to toxic metbolites Biochem
Users at their optimal level report steady results without feeling pressure to continually increase intensity
A possible explanation may suggest that this antioxidant plays a significant role in lipid metabolism, so its supplementation enhances the synthesis of fatty acids by the mammary gland in the first few days after delivery and is more present in colostrum than in mature milk [127]
Regina A, Koman A, Piciotti M, El Hafny B, Center MS, Bergmann R, Couraud PO, Roux F