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Firstly, by dampening inflammatory responses integral to the pathophysiology of depression and anxiety, omega-3 PUFAs and their metabolites can inhibit leukocyte chemotaxis, reduce the expression of adhesion molecules, decrease the production of pro-inflammatory mediators, and encourage a shift in microglia polarization towards a reparative, non-inflammatory state (75, 76)

A Phase I/II Study of Neoadjuvant Cisplatin, Docetaxel and Nintedanib for Resectable Non-Small Cell Lung Cancer