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Not enough B12 is a cause of fatigue, poor cognitive function, and is linked to increased cancer risk
However, if vitamin B 12 deficiency is the cause, it will persist despite the resolution of the anemia
Older adults may benefit from getting enough of the vitamin as it appears to play a vital role in maintaining good central vision and protecting against age-related macular degeneration
"MOTS-c can significantly enhance physical performance in young, middle-age, and old mice." Reynolds et al., Nature Communications , 2021 [3] The ceiling on all of this is the same ceiling every mitochondrial peptide hits: the outcome data is rodent data
Weight loss was primarily from fat mass rather than lean mass, and the treatment was generally well-tolerated with no significant adverse effects on glucose metabolism, insulin levels, or IGF-1 levels