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Although much of the evidence described above come from cellular fractionation studies that will need validation, these findings may explain the mitochondrial dysfunction reported in in vitro and in vivo SCA3 models, namely mtDNA deletions and reduced copy number that are often found in SCA3 cells, transgenic mice, and patients

Close vial and store on ice

Liang S, Liu Y, Zhu H, Liao G, Zhu W, Zhang L, editors

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performed an experimental study and determined PS exposure, RBC volume, cytosolic Ca 2+ activity, and ceramide formation (flow cytometer evaluation for all parameters)

Beyond its cytoplasmic transport role, ATOX1 is critically involved in vascular pathology