Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus
For therapeutic evaluation, GHRP-6, a synthetic hexapeptide with known cardioprotective and cytoprotective properties, was used
Side effects such as upper respiratory infection, low white blood cell count, and suicidality necessitate more extensive trials to confirm safety (Papp 2012
Efficacy and safety of sibutramine in obese white and African American patients with hypertension: a 1-year, double-blind, placebo-controlled, multicenter trial
Consequently, dietary intervention, as a cornerstone of lifestyle modification, is recommended as first-line therapy for all women with PCOS (96, 97)
Importantly, all reported events were self-limiting and resolved spontaneously, suggesting a favorable safety profile for natural therapies