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4-HNE and MDA not only act as the main biomarkers for lipid peroxidation assessment and contribute to multiple pathological processes during OA development

The bone is a nutrient rich environment, regulated by bone-modeling osteoclasts and osteoblasts, which drive bone osteolysis and osteogenesis, respectively

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In terms of expression in different organs, the relative expression of HrGSTm1 was highest in the Malpighian tubules, likely related to the function of the Malpighian tubules as the main excretory organ of waste

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