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Our observation of a widespread induction of pathways required for viral replication in uninfected cells, in combination with the previous detection of extracellular vesicles containing viral proteins in SARS-CoV-2 infected individuals 62,63 indicate that SARS-CoV-2 infected cells might modulate the permissibility of their microenvironment for viral replication in a similar manner
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Classified as a pentadecapeptide (15 amino acids), it functions as a signaling molecule in experimental models rather than an approved medical treatment
The vascular-modulating component, carrier pharmacokinetics and payload release profile need to be coordinated with the normalization window
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Dai J, Vrensen GF, Schlingemann RO
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