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Br J Haematol 162(5):631638

Pharmacokinetics and pharmacodynamics of the novel Nrf2 activator omaveloxolone in primates

Analyst 130:606625 Eberhardt MK (2001) Reactive oxygen metabolites

Hendrickson RG, Bizovi KE

Across multiple animal studies, commonly scaled ranges often cluster between 1 and 4 mcg per kilogram, with higher experimental rodent models occasionally translating closer to 57 mcg per kilogram