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These changes further disrupt antioxidant defense mechanisms in the brain, exacerbating age-related pathologies, including neurodegeneration and memory impairments (Singh and Kumar, 2008

[DOI] [PubMed] [Google Scholar] 40.Manea A, Tanase LI, Raicu M, Simionescu M

Known for its calming effects in the brain, it has been shown to support concentration and focus while it reduces irritability and low mood states

Additionally, patients with CD have lower levels of antioxidative substances such as plasma ascorbic acid, - and -carotene, lycopene, and -cryptoxanthin, as well as tissue GSH, which takes part in GPx-catalyzed H 2 O 2 reduction (161)

Esta doble accin antioxidante y antiinflamatoria es particularmente relevante en el contexto del inflammaging la inflamacin crnica de bajo grado asociada al envejecimiento

Kruglova MP, Ivanov AV, Fedoseev AN, Virus ED, Stupin VA, Parfenov VA, et al