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25 The first line includes superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx), which encompass cytosolic SOD1 and mitochondrial matrix SOD2 that remove O 2 , catalases, and GPxs that eliminate H 2 O 2 , and certain GPxs and PRDXs that reduce lipid peroxides

Meanwhile, the mechanism of binding of PKUMDL- LDL-102 has been studied using molecular docking and detected as an hGPX4-C activator [8]

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Conversely, inhibitors of PD-1/PD-L1 can selectively attach to either PD-1 or PD-L1, thereby interfering with the PD-1/PD-L1 interaction

PMCID: PMC4406448

After 24 h the colonies on the plates were counted and numbers expressed as CFU/ml