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Doses above 100mg daily show diminishing returns in NNMT inhibition the enzyme inhibition curve plateaus beyond 150mg while increasing the risk of methylation pathway disruption and homocysteine elevation

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For example, a 10mg/mL solution is often easier to dose accurately than a 50mg/mL solution

Therefore, for anyone considering such a combination, the following apply: Extreme Caution and Medical Supervision: This is not a self-experimentation endeavor

this alone is enough reason for people to choose a drop-form of the supplement which they have to take on a daily basis