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A 2021 study on nalfurafine, a -opioid agonist metabolized by cytochrome P450 into an inactive form, showed significant improvement in pruritus scores without notable adverse effects at doses of 2.5 mg and 5 mg, regardless of daytime or nighttime itching (24)

Diagnosed B12 deficiency: Symptoms include fatigue, pale skin, shortness of breath, tingling in hands/feet, and mood changes

He was 48 years old

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Protein-based nanoparticles: From preparation to encapsulation of active molecules