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lysosomal signalling molecules regulate longevity in Caenorhabditis elegans

12 A blunted CAR and flattening of the diurnal cortisol curve, or hypothalamicpituitaryadrenal (HPA) axis dysregulation, is also associated with insulin resistance, depression, and stress

Specifically, it up-regulates CPT1 mRNA expression, thereby promoting mitochondrial fatty acid transport and enhancing -oxidation activity (25, 26)

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Scientists therefore cannot conclude that these blends produce the same biological effects in humans